I generally don't care for Fords, but I know of a F150 with over 400,000 miles that is still running. Not sure of the engine, but it is a V-8, it might be a 92 or so year truck. Survived 2 teenage drivers, as well.

I know another guy with a 2000 F250 that he used hard pulling on a farm, he got 60,000 or so out of the original motor(might have been the 5.4), then he had a Cummins installed. He likes the truck a lot better now.