If go west on Iowa 2 from waterloo, would be coming down South on I-35..............take I-35 to southwest corner of DesM. 

Take Iowa 5  east.

Get off on Fleur Drive...........and go north.

In about 2 miles or less, the airport is on the west side of Fleur.

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But if come down on I-280 to Iowa City, and take I-80 west to Des Moines..................

Then get off at US 65 and go south..............4 lane.         Exit is second exit.....about 1 mile or less........ just past Ziegler Cat.

US 65 turns into Iowa 5.........and turns west...........you won't notice the combo.

Get off on Fleur Drive...........and go north.

In about 2 miles or less, the airport is on the west side of Fleur.

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 Exit onto Fleur for airport is well-marked.

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Long term parking is the last entrance to the ramp..............short term parking is in same entrance, but bear left.