n. Illinois | hlstark - 12/27/2022 15:31
This is a direct quote from that study in the summary
In a cohort of vaccinees with breakthrough infections, we did not obtain any evidence for an alteration of disease severity, which was mild in almost all of our cases.
This means that even with their findings, the Covid breakthrough cases were mild and did not make anyone get sicker from Covid even after repeated shots. Not much for breaking news
It went on to say this.
Larger cohorts with differential disease severities will be needed to address this aspect in the future. However, our results clearly demonstrate that a subsequent infection can further boost IgG4 antibody levels, with IgG4 becoming the most dominant among all anti-spike IgG subclasses in some individuals
It also said this.
Importantly, this class switch was associated with a reduced capacity of the spike-specific antibodies to mediate antibody-dependent cellular phagocytosis and complement deposition. Since Fc-mediated effector functions are critical for antiviral immunity, these findings may have consequences for the choice and timing of vaccination regimens using mRNA vaccines, including future booster immunizations against SARS-CoV-2.
This is a very unreadable (unless you study immuniology) study but the people who do study this field think its big deal.
here is a video of the experts discussing such an outcome (from 2020) so they know it was a possibility which means they needed to make sure it didn't happen.
https://metatron.substack.com/p/the-worst-possible-thing-you-could
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IgG
